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Biology 5090 · Chapter 8

Human Nutrition

Diet and deficiency diseases, the human digestive system, teeth, enzymes and digestion, bile, peristalsis, and absorption and assimilation in the small intestine.

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8.1 Diet

A balanced diet contains all the nutrients in the correct amounts for energy and health: carbohydrates, lipids, proteins, vitamins, minerals, fibre and water. How much is needed depends on age, sex, activity level and whether a woman is pregnant or breast-feeding.

NutrientMain sourcesImportance
carbohydratesbread, rice, potatoes, pasta, sugarthe main source of energy
lipids (fats and oils)butter, oil, nuts, meat, fisha store of energy, insulation, and part of cell membranes
proteinsmeat, fish, eggs, beans, milkgrowth and repair of tissues; make enzymes and hormones
vitamin Ccitrus fruits, tomatoes, green vegetableskeeps skin and gums healthy; helps wounds heal
vitamin Doily fish, eggs, milk; made in the skin in sunlighthelps the body absorb calcium, for strong bones and teeth
calciummilk, cheese, green vegetablesstrong bones and teeth
ironred meat, liver, spinachmakes haemoglobin in red blood cells
fibre (roughage)vegetables, fruit, whole grainsgives bulk to the food so that peristalsis can push it along, preventing constipation
waterdrinks and fooda solvent; makes up blood plasma, cytoplasm and urine; needed for all chemical reactions

Deficiency diseases

Missing nutrientDiseaseSymptoms
vitamin Cscurvybleeding gums, slow healing of wounds, loose teeth
vitamin Dricketssoft, weak bones that bend (bow legs) in children
calciumricketssoft, weak bones, and weak teeth
ironanaemianot enough haemoglobin, so tiredness, weakness and pale skin

8.2 Human digestive system

The human digestive system, showing the mouth, salivary glands, oesophagus, stomach, liver, gall bladder, pancreas, small intestine and large intestine

The human digestive system, showing the mouth, salivary glands, oesophagus, stomach, liver, gall bladder, pancreas, small intestine and large intestine

Why food must be digested

Most food molecules are large and insoluble, so they cannot pass through the wall of the gut into the blood. They must be digested into small, soluble molecules that can be absorbed.

  • Physical digestion is the breakdown of food into smaller pieces without chemical change to the food molecules (chewing and the churning of the stomach). It increases the surface area of the food for enzymes to act on.
  • Chemical digestion is the breakdown of large molecules into small molecules by enzymes.

Teeth

The structure of a human tooth, showing enamel, dentine, pulp with nerves and blood vessels, cement and the gum

The structure of a human tooth, showing enamel, dentine, pulp with nerves and blood vessels, cement and the gum
TypeFunction in physical digestion
incisorscutting and biting food
caninestearing and piercing food
premolarscrushing and grinding food
molarscrushing and grinding food

Parts of a tooth: enamel (the hard outer covering of the crown), dentine (a bone-like layer beneath it), pulp (the soft centre with nerves and blood vessels), and cement (which fixes the root into the jaw). Teeth are embedded in the gum.

The regions of the digestive system

RegionFunction
mouthingestion; physical digestion by teeth; chemical digestion of starch by amylase in saliva
salivary glandssecrete saliva containing amylase
oesophaguscarries food to the stomach by peristalsis
stomachphysical digestion (churning); chemical digestion of protein by protease (pepsin); secretes hydrochloric acid
small intestine (duodenum and ileum)chemical digestion of starch by amylase, maltose by maltase, protein by protease and lipids by lipase; absorption of nutrients in the ileum
livermakes bile; stores glycogen
gall bladderstores bile
pancreassecretes an alkaline juice containing amylase, protease and lipase into the duodenum
large intestine (colon)absorbs water (and some ions)
rectum and anusthe rectum stores faeces and the anus egests them

The digestive enzymes

EnzymeSubstrateProductsWhere
amylasestarchmaltosemouth (saliva) and small intestine (from the pancreas)
maltasemaltoseglucosesmall intestine
protease (pepsin and trypsin)proteinamino acidspepsin in the stomach; trypsin in the small intestine
lipaselipids (fats and oils)fatty acids and glycerolsmall intestine (from the pancreas)
  • Hydrochloric acid in the stomach kills bacteria that are eaten with the food, and provides the acid conditions (about pH 2) in which pepsin works best.
  • The proteases in the stomach and the duodenum work best at different pH values: pepsin in acid and trypsin in the alkaline conditions of the small intestine (the pancreatic juice and bile neutralise the acid from the stomach).

Bile

Bile does not contain enzymes, and it does not chemically digest fat.

Peristalsis

The circular muscles contract behind the food, narrowing the gut, while the longitudinal muscles contract to shorten that section; the muscles ahead of the food relax, so the food moves forwards.

Amylase breaks starch down to maltose. Maltase, in the small intestine, breaks maltose down to glucose.

8.3 Absorption and assimilation

The small intestine (mainly the ileum) is where most nutrients are absorbed. Absorption happens by diffusion, osmosis and active transport. Water is absorbed in the small intestine and the colon, but most of the water is absorbed in the small intestine.

Villi

The inner wall of the ileum is covered in many tiny finger-like projections called villi. The cells on their surface have even smaller projections called microvilli.

A villus in the ileum, showing the thin wall of one cell thick, a network of capillaries, and a lacteal

A villus in the ileum, showing the thin wall of one cell thick, a network of capillaries, and a lacteal
Feature of a villusFunction
villi and microvillia very large internal surface area for absorption
a wall one cell thicka short diffusion distance
a network of capillariesa good blood supply that takes away glucose and amino acids, keeping a steep concentration gradient
a lacteal (a lymph vessel)absorbs fatty acids and glycerol

The hepatic portal vein

The liver then regulates what reaches the rest of the body: it stores glucose as glycogen, turns excess amino acids into urea, and removes toxins.

Assimilation

The nutrients that are carried in the blood are used by the cells: glucose in respiration, amino acids to build proteins, and fatty acids and glycerol to make cell membranes and for energy storage.

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